Endocrine Abstracts

Introduction: Endogenous Cushing’s disease is a serious and rare endocrine disorder. Medical therapy is mostly used as second-line treatment after failed surgery or recurrence and comprises several pituitary-directed drugs, glucocorticoid receptor blocker and adrenal steroidogenesis inhibitors such as osilodrostat. We here describe a case of a Tunisian patient with uncured cushing’s disease who developed iatrogenic adrenal insufficiency in the setting of Osilodrostat...